Description
T helper (Th) cells provide helper functions to other cells in regulating immune responses. They secrete cytokines to stimulate various effector cells, such as cytotoxic T cells, B cells, and macrophages, and play an important role in the activation and maturation of these cells. These cytokines have also been linked to inflammation and autoimmune diseases. There are different subsets of CD4+ Th cells, including Th1, Th2, Th17 and regulatory T cells (Tregs). Each subpopulation is activated by a specific set of cytokines and transcription factors and is characterized by the cytokines they secrete and the effector functions they exert.
Accurate measurement of Th the expression of cytokines for insight into the immune response and many disease processes is very important. Creative Proteomics offers microbead-based multiplex detection panels that allow the quantitative analysis of multiple analytes from a small number of samples.
Detection Method
Magnetic bead-based Luminex multiplex assay
Species
Mouse
Transportation
Wet ice
Analytes Detected
| Species | Analysis Targets | Specification | Protein Targets | Price |
|---|---|---|---|---|
| Mouse | Th1/Th2 | Mouse Th1/Th2 cytokine 6-plex Panel | IFNγ, IL-4, IL-5, IL-6, IL-12p70, TNF-α | +Inquiry |
| Mouse Th1/Th2 Cytokine 7-plex Panel | IFN-g, IL-1b, IL-2, IL-6, IL-10, IL-12(p70), TNF-α | +Inquiry | ||
| Mouse Th1/Th2 Cytokine 7-plex Panel | IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, L-13 | +Inquiry | ||
| Mouse Th1/Th2 Cytokine 8-plex Panel | IL-2, IL-4, IL-5, IL-10, IL-12 (p70), GM-CSF, IFN-γ, TNF-α | +Inquiry | ||
| Mouse Th1/Th2 Cytokine 11-plex Panel | GM-CSF, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-12p70, IL-13, IL-18, TNF-α | +Inquiry | ||
| Mouse Th1/Th2 Cytokine 20-plex Panel | Eotaxin, GROα/KC/CXCL1, GM-CSF, IFNγ, IL-1β, L-2, IL-4, IL-5, IL-6, IL-12p70, IL-13, IL-18, IP-10, MCP-1, MCP-3, MIP-1α, MIP-1β, MIP-2, RANTES, TNFα | +Inquiry | ||
| Mouse | Th17 | Mouse Th17 Cytokine 6-Plex Panel | IL-1β, IL-4, IL-6, IL-10, IL-17A, IFN-γ, TNF-α. | +Inquiry |
| Mouse Th17 Cytokine 8-Plex Panel | CD40L, IL-17F, IL-21, IL-22, IL-23p19, IL-31, IL-33, MIP-3α | +Inquiry | ||
| Mouse Th17 Cytokine 25-Plex Panel | L-4, IL-5, IL-6, IL-10, IL-12 (p70), L-13, L-15, IL-17A/CTLA8, L-17E/IL-25, IL-17F, IL-1β, IL-2, IL-21, IL-22, IL-23, IL-27, IL-28B/IFNλ3, IL-31, IL-33, IFNγ, GM-CSF, MIP-3α/CCL20, sCD40L, TNFα, TNFβ | +Inquiry | ||
| Mouse | Treg | Mouse Treg Cytokine 6-Plex Panel | IL-9, IL-10, IL-17A, IL-22, IL-23, IL-27 | +Inquiry |
| Mouse Treg Cytokine 15-Plex Panel | IL-10, IL-17A, IL-22, IL-23, IL-27, IL-9, GROα, IP-10, MCP-1, MCP-3, MIP-1α, MIP-1β, MIP-2, RANTES, Eotaxin | +Inquiry | ||
| Mouse Treg Cytokine 17-Plex Panel | GM-CSF, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17A, IL-18, IL-22, IL-23, IL-27, TNFα | +Inquiry |
Service Features
- 96-well plate design for batch detection of multiplexed factors up to 80 samples
- High sensitivity, as low as pg/mL
- Multi-factor assays performed with 50 μL liquid sample and 200 μg total protein
- Suitable for serum/plasma, culture supernatants, cells, tissue lysates.
- Maximized information in a single sample and cross-analysis allowed between analytes
- Run your assay in just 3-5 hours
- Mass-calibrated standards for consistent results with every new lot of material
Suggested Application
- Multiplexed protein assays
- Relative protein expression assays
- Detection of cytokine expression patterns
- Biomarker/key factor screening
- Identification of key factors
- Confirmation of biological processes