Cancer biomarkers are substances produced directly by tumor cells or by non-tumor cells induced by tumor cells. For the detection of tumor markers can make a judgment on tumor existence, pathogenesis and prognosis.
One of the major challenges in cancer prevention and treatment is early diagnosis and effective intervention. Finding cells in a certain physiological state, biochemical or molecular changes will be able to serve as markers to detect and evaluate biological processes. For example, when a normal cell transforms into a cancerous state, biomarkers can send key molecular signals for diagnosis, prognosis, and the development of more effective treatments.
While there are a number of individual biomarkers that are critical to the research diagnosis of cancer, a single biomarker is unlikely to serve as decisive clinical data on the nature or progression of the disease. In contrast, a combination of biomarkers can provide more sensitive and targeted information for accurate diagnosis or prognosis.
Creative Proteomics offers several optional Luminex Human Cancer Biomarker Panels to study cancer biomarkers in serum, plasma, urine and cell supernatants. We base on Luminex xMAP technology to achieve ideal speed and sensitivity for simultaneous quantification of multiple analytes, significantly increasing productivity and saving valuable sample volumes. Analyzing multiple analytes together is an important tool for researchers to be able to measure cancer biomarkers simultaneously, sort out these relationships, and apply them to understanding tumor biology.
Magnetic bead-based Luminex multiplex assay
|Human||Human Cancer Biomarker 5-plex Panel||Antithrombin III, Complementary factor H (CFH), Extracellular matrix protein 1 (ECM1), Vitamin D binding protein, Vitronectin||+Inquiry|
|Human||Human Cancer Biomarker 8-plex Panel||Cathepsin D, Ferritin, Fibroblast activation protein (FAP), Galectin3, IGFBP3, Melanoma inhibitory activity (MIA), Myeloperoxidase (MPO), Sex hormone-binding globulin||+Inquiry|
|Human||Human Cancer Biomarker 9-plex Panel||DKK1, GDF15, Neuron-specificenolase (NSE), Osteonectin (SPARC), Osteoprotegerin (OPG), Periostin, TRAP, TWEAK, YKL40||+Inquiry|
|Human||Human Cancer Biomarker 10-plex Panel||ALDH1A1, Carbonic Anhydrase 9, CD44, EpCAM, Hepsin, Kallikrein-6, Mesothelin, Midkine, NCAML/L1CAM/CD171, Transglutaminase 2 (TGM2)||+Inquiry|
|Human||Human Cancer Biomarker 24-plex Panel||CA125, CA15-3, CA19-9, CEA, CYFRA21-1, FGF-2/FGF-basic, HCGβ, HE4, HGF, IL-6, IL- 8/CXCL8, Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (total), SCF, sFas, sFasL/TNFRSF6, TGFα, TNFα, TRAIL/TNFSF10, VEGF-A, α-Fetoprotein (AFP)||+Inquiry|
- 96-well plate design for batch detection of multiplexed factors up to 80 samples
- High sensitivity, as low as pg/mL
- Multi-factor assays performed with 50 μL liquid sample and 200 μg total protein
- Suitable for serum/plasma, culture supernatants, cells, tissue lysates
- Maximized information in a single sample and cross-analysis allowed between analytes
- Run your assay in just 3-5 hours
- Mass-calibrated standards for consistent results with every new lot of material
Application of Cancer Biomarker Hormone Panel
- Multiplexed protein assays
- Relative protein expression assays
- Detection of cytokine expression patterns
- Biomarker screening
- Identification of key factors
- Confirmation of biological processes