Description

Inflammation-associated factors are an important class of cytokines involved in the immune regulation of inflammatory responses and their mediated diseases. When the body is exposed to a noxious stimulus (e.g., tissue damage or foreign antigens), resident immune cells initiate and then trigger inflammation mediated by the action of various cytokines and chemokines. The course of the inflammatory response depends on the balance between pro-inflammatory and anti-inflammatory mediators. Pro-inflammatory cytokines are responsible for the early response and amplify the inflammatory response, while anti-inflammatory cytokines limit the inflammatory response. Abnormal inflammation underlies many chronic human diseases. Therefore, accurate measurement of inflammatory mediators helps to understand the role played by these inflammatory molecules in the immune response.

Creative Proteomics offers the Luminex Human Inflammation 20-plex/24-plex/25-plex/27-plex/37-plex/48-plex Panel for quantifying human Inflammation factors in serum, plasma, tissue culture supernatants and cultured cells to meet your diverse needs. Base on Luminex xMAP technology, we can achieve ideal speed and sensitivity for simultaneous quantification of multiple analytes, significantly increasing productivity and saving valuable sample volumes.

Detection Method

Magnetic bead-based Luminex multiplex assay

Species

Human

Transportation

Wet ice

Analytes Detected

SpeciesSpecificationProtein TargetsPrice
HumanHuman Inflammation 20-plex PanelIL-12, CCL2, CCL3, CCL4, CD54, CXCL10, GM-CSF, IFNα, IFNγ, IL-1α, IL-1β, IL-10, IL-13, IL-17A, IL-4, IL-6, IL-8, sCD62E, sCD62P, TNFα+Inquiry
HumanHuman Inflammation 24-plex PanelAPRIL/TNFSF13, BAFF/TNFSF13B, Chitinase-3-like1, gp130/sIL-6Rβ, IFN-β, IL-11, IL-19, IL-20, IL-26, IL-27(p28), JIL-28A/IFN-λ2, IL-29/IFN-λ1, IL-32, IL-34, IL-35, LIGHT/TNFSF14, Osteocalcin, Pentraxin-3. sCD163, sCD30/TNFRSF8, sTNF-R1, sTNF-R2, TSLP, TWEAK/TNFSF12+Inquiry
HumanHuman Inflammation 25-plex PanelCCL2/MCP-1, CCL3/MIP-1α, CCL4MIP-1β, CCL11/Eotaxin, CCL24/Eotaxin-2, CXCL8/IL-8, CXCL9/MIG, CXCL13/BLC, G-CSF, GM-CSF, ICAM-1, IFN-γ, IFN-γR1, IL-1α, IL-1Ra, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12(p70), IL-15, M-CSF, TNF-α, TNFRI+Inquiry
HumanHuman Inflammation 27-plex PanelFGF basic, Eotaxin, G-CSF, GM-CSF, IFN-y, IL-1B, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12(p70), IL-13, IL-15, IL-17, IL-17 IP-10, MCP-1(MCAF), MIP-1c, MIP-13, PDGF-BB, RANTES, TNF-a, VEGF+Inquiry
HumanHuman Inflammation 37-plex PanelAPRIL/TNFSF13, BAFF/TNFSF13B, Chitinase-3-like1, gp130/sIL-6Rβ, IFN-α2, IFN-β, IFN-γ, IL-2, IL-8, IL-10, L-11, IL-12(p40), IL-12(p70), IL-19, IL -20, L-22, IL-26, L-27(p28), IL-28A/IFN-λ2, IL-29/IFN-λ1, IL-32, IL-34, IL-35, LIGHT/TNFSF14, MMP-1, MMP-2, MMP-3, Osteocalcin, Osteopontin, Pentraxin-3, sCD163, sCD30/TNFRSF8, sIL-6Rα, sTNF-R1, sTNF-R2, TSLP, TWEAK/TNFSF12+Inquiry
HumanHuman Inflammation 48-plex PanelIL-1α, IL-2Rα, IL-3, IL-12 (p40), IL-16, IL-18, CTACK, GRO-α, HGF, IFN-α2, LIF, MCP-3, M-CSF, MIF, MIG, β-NGF, SCF, SCGF-3, SDF-1α, TNF-β, TRAIL, FGF basic, Eotaxin, G-CSF, GM-CSF, IFN-γ, IL-1β, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p70), IL 13, IL-15, IL-17, IP-10, MCP-1 (MCAF), MIP-1α, MIP-1β, PDGF-BB, RANTES, TNF-α, VEGF+Inquiry

Service Features

  • 96-well plate design for batch detection of multiplexed factors up to 80 samples
  • High sensitivity, as low as pg/mL
  • Multi-factor assays performed with 50 μL liquid sample and 200 μg total protein
  • Suitable for serum/plasma, culture supernatants, cells, tissue lysates, some panels can also be validated with breast milk, saliva and/or urine samples
  • No batch-to-batch errors
  • Maximized information in a single sample and cross-analysis allowed between analytes
  • Run your assay in just 3-5 hours
  • Mass-calibrated standards for consistent results with every new lot of material

Service Features

Suggested Application

  • Multiplexed protein assays
  • Relative protein expression assays
  • Detection of cytokine expression patterns
  • Biomarker/key factor screening
  • Identification of key factors
  • Confirmation of biological processes
* For Research Use Only. Do Not use in diagnostic or therapeutic procedures.

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